We work where human biology meets engineering

Human-relevant aged tissue models

Preclinical service utilizing novel organ-on-a-chip technology to mimic an aged environment

What do we offer?

Aging-on-Chip Services

We induce aging using an organ-on-a-chip environment, validate the aged state, and run your studies across multiple readouts.

Pick your cell line

In-house

  • Adipose
  • Liver
  • Adipose & Liver (Multi-tissue system)

Your own

We'll adapt your SOPs to an organ-on-a-chip environment

Age & validate on-chip

Induction in an organ-on-a-chip microphysiological environment, then marker verification:

  • SA-β-gal
  • IL6
  • TNF
  • CDKN1A (p21)
  • CDKN2A (p16)

Run your studies

Research, toxicology, and drug-performance studies with orthogonal readouts:

  • qPCR (CDKN1A/CDKN2A)
  • SA-β-gal staining & imaging
  • Proteomics (SASP profiling)
  • Mass spectrometry
Blue Chip Bio MPS

Our Technology

  • Multi-tissue organ-on-a-chip technology
  • Closely mimics human biology
  • Accurate artificial aging platform
  • Reduced reliance on animal testing
  • Highly standardized, reproducible protocol

Comparison of Preclinical Methods

Feature comparison across in vitro 2D culture, in vivo animal models, and microphysiological systems.
In vitro 2D Cell Culture In vivo Animal Model Microphysiological System
Human relevance
Complex 3D organs and tissues
Customizable models
Rapid inducible aging
Time to result FAST SLOW FAST
Throughput

Founding principles

Decisions should be grounded in systems that mirror human biology.

Age matters

Preclinical data often fails to account for aged physiology

Faster therapies

Our platform enables rapid discovery of vital longevity medicines

Human-like models

Decisions should be based on systems that closely mimic human biology

Ethical by design

The future of preclinical research is 100% animal-free

Founding team

People behind the platform

Dr. Cameron Kato headshot

Dr. Cameron Kato

CSO, Co-Founder Ph.D. Bioengineering and Biomedical Engineering University of California, Berkeley & UCSF
ckato@berkeley.edu

Prof. Andreas Stahl headshot

Dr. Andreas Stahl

CTO, Co-Founder Professor of Nutritional Sciences & Toxicology University of California, Berkeley
astahl@berkeley.edu

Prof. Irina Conboy headshot

Dr. Irina Conboy

Scientific Advisory Board Member Professor of Bioengineering University of California, Berkeley
iconboy@berkeley.edu

Previously at

UC Berkeley UCSF Stanford Stanford School of Medicine MIT Whitehead Institute Scripps Research CIRM NSF I-Corps Nucleate UC Berkeley SkyDeck QB3

Contact Us

Need to reach out directly? Email declanfarriday@berkeley.edu.

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